Sodium valproate

Chemical Formula: C₈H₁₅NaO₂

Molecular Weight: 166.196

CAS Number: 1069-66-5

Description: Sodium valproate USP, White solid, ≥98.0% (NMR spectroscopy)

Valproic acid, or valproate, is a fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. It first received approval on February 28, 1978 from the FDA under the trade name Depakene. Since then, it has been investigated for neuroprotective, anti-manic, and anti-migraine effects. It is currently a compound of interest in the field of oncology for its anti-proliferative effects and is the subject of many clinical trials in a variety of cancer types.